locus

BSU12910

BSU_12910

geneLength

816

819

outlinks

bsu

BSU12910

BSU_12910

Gene

Coordinates

1,359,454 → 1,360,272

1,359,454 1,360,272

The protein

Catalyzed reaction/ biological activity

1-pyrroline-5-carboxylate + NADPH + H⁺ --> L-proline + NADP⁺ [pubmed|28824574]

L-proline + NADP⁺ --> 1-pyrroline-5-carboxylate + 2 H⁺ + NADPH (according to UniProt)

L-proline + NAD⁺ --> 1-pyrroline-5-carboxylate + 2 H⁺ + NADH (according to UniProt)

The protein

Protein family

pyrroline-5-carboxylate reductase family (according to Swiss-Prot)

[SW|pyrroline-5-carboxylate reductase family] [pubmed|28824574]

Biological materials

Mutant

MGNA-B308 (ykeA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1307 NBRP B. subtilis, Japan]

BKE12910 ([[gene|proG]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE12910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGACTCAGTCCTTTCAT, downstream forward: _UP4_TGAATCCTTGAAAGAGGATT

BKK12910 ([[gene|proG]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK12910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGACTCAGTCCTTTCAT, downstream forward: _UP4_TGAATCCTTGAAAGAGGATT

The protein

Paralogous protein(s)

[[this]]

The protein

Effectors of protein activity

feedback-inhibited by proline [pubmed|28824574]